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Antibodies

UNC5H3

Product Sizes
100 ug
£674.12
101-M696-100UG
About this Product
SKU:
101-M696
Additional Names:
UNC5C; UNC5H3
Application:
IHC-Paraffin, Western Blot
Buffer:
PBS
translate.label.attr.clone:
7F31
Clonality:
Monoclonal
Extra Details:
Members of the UNC5H family are best known as receptors for the axon guidance molecule netrin. Structurally, UNC5Hs have two Ig and two thrombospondin type 1 domains in their extracellular region, and a conserved ZU-5 domain, a deleted in colorectal cancer (DCC)-binding domain, and a C-terminal death domain in their cytoplasmic region. In general, they mediate the chemorepulsive effects of netrin, while the other netrin receptor subtype, DCC, mediates attraction. Members of the UNC5H family have also been implicated as tumor suppressors and regulators of apoptosis.
Formulation:
lyophilized
Host:
Mouse
Immunogen:
recombinant human UNC5H3 EC domain
Isotype:
IgG2
Purification:
Protein G Purified
Reactivities:
Human
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C lyophilized. Avoid freeze/thaw cycles.
Supplier:
ReliaTech
Type:
Antibody: Monoclonal Antibody