NKp46
Product Sizes
100 ug
£674.12
101-M587-100UG
About this Product
- SKU:
- 101-M587
- Additional Names:
- NCR1; LY94; CD335; NKP46; NK-p46
- Application:
- Flow Cytometry, IHC-Frozen, Western Blot
- Buffer:
- PBS
- translate.label.attr.clone:
- 8F24
- Clonality:
- Monoclonal
- Extra Details:
- NKp30/NCR3, NKp44/NCR2, and NKp46/NCR1 are termed natural cytotoxicity receptors (NCR). These receptors are type I transmembrane proteins with 1-2 extracellular immunoglobulin domains, a transmembrane domain containing a positively charged amino acid residue, and a short cytoplasmic tail. All are expressed almost exclusively by NK cells and play a major role in triggering NK-mediated killing of most tumor cell lines. NKp44 is induced upon activation of resting NK cells with IL-2 and can bind to viral hemagglutinins. NK-mediated dendritic cell (DC) recognition is highly dependent on engagement of NKp30 and may result in lysis of the DC.
- Formulation:
- lyophilized
- Host:
- Mouse
- Immunogen:
- recombinant human NKp46
- Isotype:
- IgG2
- Purification:
- Protein G Purified
- Reactivities:
- Human
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C lyophilized. Avoid freeze/thaw cycles.
- Supplier:
- ReliaTech
- Type:
- Antibody: Monoclonal Antibody