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Antibodies

DLL4

Product Sizes
100 ug
£674.12
101-M527-100UG
About this Product
SKU:
101-M527
Additional Names:
DLL4; hdelta3
Application:
Immunohistochemistry, Western Blot
Buffer:
PBS
translate.label.attr.clone:
28V45
Clonality:
Monoclonal
Extra Details:
Human sDLL4 comprises the extracellular signaling domain of DLL, a member of a structurally-related family of single-pass type I trans-membrane proteins that serve as ligands for Notch receptors. DLL4 functions to specifically activate the Notch-1 and Notch-4 receptors. The Notch signaling pathway regulates endothelial-cell differentiation, proliferation and apoptosis, and is essential for the development, maintenance and remodeling of the vascular system. Targeted deletion of the DLL4 gene in mice resulted in severe vascular defects and death before birth. Up-regulation of DLL4 expression has been implicated in the vascular development of certain tumors. Recombinant human sDLL4 is a 54.0 kDa glycoprotein containing 498 amino-acid residues.
Formulation:
lyophilized
Host:
Rat
Immunogen:
Recombinant Human DLL4
Isotype:
IgG2
Purification:
Protein G Purified
Reactivities:
Human
Shipping Conditions:
Ambient
Storage Conditions:
-70[o]C lyophilized. Avoid freeze/thaw cycles.
Supplier:
ReliaTech
Type:
Antibody: Monoclonal Antibody