IL-18 receptor beta
Product Sizes
100 ug
£674.12
101-M494-100UG
About this Product
- SKU:
- 101-M494
- Additional Names:
- IL18RAP; ACPL; CD218b; IL18RB; CDw218b
- Application:
- Block/Inhibit/Neutralise, Western Blot
- Buffer:
- PBS
- translate.label.attr.clone:
- 10D34
- Clonality:
- Monoclonal
- Extra Details:
- The functional IL-18 receptor complex is composed of two subunits designated IL-18 R alpha (also termed IL-1 R5 and IL-1 Rrp) and IL-18 R beta (also termed IL-1 R7 and AcPL). Both IL-18 R alpha and IL-18 R beta belong to the IL-1 receptor family. Although IL-18 R alpha by itself binds IL-18 with low-affinity and IL-18 R beta does not bind IL-18 in vitro, co-expression of IL-18 R alpha and IL-18 R beta is required for high-affinity binding and IL-18 responsiveness. IL-18 R is widely expressed in numerous tissues including spleen, thymus, leukocyte, liver, lung, heart, small and large intestine, prostate and placenta. It is not expressed in brain, skeletal muscle, kidney and pancreas.
- Formulation:
- lyophilized
- Host:
- Mouse
- Immunogen:
- recombinant human IL-18 R alpha EC domain
- Isotype:
- IgG1
- Purification:
- Protein G Purified
- Reactivities:
- Human
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C lyophilized. Avoid freeze/thaw cycles.
- Supplier:
- ReliaTech
- Type:
- Antibody: Monoclonal Antibody