GMF-beta
Product Sizes
100 ug
£674.12
101-M436-100UG
About this Product
- SKU:
- 101-M436
- Additional Names:
- GMFB; GMF
- Application:
- Western Blot
- Buffer:
- PBS
- translate.label.attr.clone:
- 8X12
- Clonality:
- Monoclonal
- Extra Details:
- The high affinity receptor for granulocyte-macrophage colony stimulating factor (GM-CSF) consists of two subunits; an 80 kDa cytokine-specific alpha-subunit (CD116), and a 120 kDa non-specific, signal transducing beta-subunit (CD131). Analogous with other cytokine signaling mechanisms, CD131 is also shared with the cytokine specific alpha-subunits of the IL-3 and IL-5 receptors. In the absence of CD131, the CD116 alpha-subunit binds GM-CSF with low affinity. GM-CSF receptors are highly expressed on neutrophils, monocytes, oligodendrocytes, megakaryocytes, eosinophils, and myeloid leukemia cells.
- Formulation:
- lyophilized
- Host:
- Mouse
- Immunogen:
- recombinant human GMF-beta
- Isotype:
- IgG2
- Purification:
- Protein G Purified
- Reactivities:
- Human
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -70[o]C lyophilized. Avoid freeze/thaw cycles.
- Supplier:
- ReliaTech
- Type:
- Antibody: Monoclonal Antibody