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Antibodies

FGF-3

Product Sizes
100 ug
£674.12
101-M408-100UG
About this Product
SKU:
101-M408
Additional Names:
FGF3; INT2; HBGF-3
Application:
Block/Inhibit/Neutralise, IHC-Paraffin, Western Blot
Buffer:
PBS
translate.label.attr.clone:
3F18
Clonality:
Monoclonal
Extra Details:
Fibroblast Growth Factor 3 (FGF3) belongs to the large FGF family which has at least 23 members. All FGF family members are heparinbinding growth factors with a core 120 amino acid (aa) FGF domain that allows for a common tertiary structure. FGFs are expressed during embryonic development and in restricted adult tissues. They act on cells of mesodermal and neuroectodermal origin to regulate diverse physiologic functions including angiogenesis, cell growth, pattern formation, embryonic development, metabolic regulation, cell migration, neurotrophic effects and tissue repair. Signaling receptors for FGFs are type I transmembrane receptor tyrosine kinases belonging to the Ig superfamily. Four distinct but related classes of FGF receptors, FGF R1, 2, 3, and 4, exist. Through alternative splicing, multiple isoforms for FGF R1, 2 and 3, with distinct ligand recognition profiles, are also generated. The FGF3 gene, originally designated int2, was first identified as a protooncogene activated in mouse mammary tumors by proviral integration.
Formulation:
lyophilized
Host:
Mouse
Immunogen:
Recombinant human FGF-3
Isotype:
IgG2
Purification:
Protein G Purified
Reactivities:
Human
Shipping Conditions:
Ambient
Storage Conditions:
-70[o]C lyophilized. Avoid freeze/thaw cycles.
Supplier:
ReliaTech
Type:
Antibody: Monoclonal Antibody