CTLA-4
Product Sizes
100 ug
£674.12
101-M345-100UG
About this Product
- SKU:
- 101-M345
- Additional Names:
- CTLA4; CD; GSE; GRD4; ICOS; CD152; CTLA-4; IDDM12; CELIAC3
- Application:
- Western Blot
- Buffer:
- PBS
- translate.label.attr.clone:
- 8F16
- Clonality:
- Monoclonal
- Extra Details:
- CD28 and CTLA-4, together with their ligands, B7-1 and B7-2, constitute one of the dominant costimulatory pathways that regulate T and B cell responses. CD28 and CTLA-4 are structurally homologous molecules that are members of the immunoglobulin (Ig) gene superfamily. CTLA-4 is up-regulated rapidly following T cell activation and CD28 ligation. Although both CTLA-4 and CD28 can bind to the same ligands, CTLA-4 binds to B7-1 and B7-2 with a 20-100 fold higher affinity than CD28.
- Formulation:
- lyophilized
- Host:
- Mouse
- Immunogen:
- human recombinant CTLA-4
- Isotype:
- IgG2
- Purification:
- Protein G Purified
- Reactivities:
- Human
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -70[o]C lyophilized. Avoid freeze/thaw cycles.
- Supplier:
- ReliaTech
- Type:
- Antibody: Monoclonal Antibody