CLN-2
Product Sizes
100 ug
£674.12
101-M327-100UG
About this Product
- SKU:
- 101-M327
- Additional Names:
- TPP1; CLN2; GIG1; LPIC; TPP-1
- Application:
- Western Blot
- Buffer:
- PBS
- translate.label.attr.clone:
- 9V1
- Clonality:
- Monoclonal
- Extra Details:
- Tripeptidyl-peptidase I (TPP1), also known as CLN2, is a lysosomal serine protease detected in all tissues examined, with highest levels shown in heart and placenta. It is an aminopeptidase that cleaves tripeptides from the free N-terminus of polypeptides and may also have endopeptidase activity. Defects in TPP1 are the cause of classical late-infantile neuronal ceroid lipofusionosis, also known as ceroid lipofusionosis neuronal 2 (CLN2), a fatal childhood neurodegenerative disease characterized by progressive visual and mental decline, motor disturbance, epilepsy, and behavioral changes.
- Formulation:
- lyophilized
- Host:
- Mouse
- Immunogen:
- recombinant human CLN-2
- Isotype:
- IgG2
- Purification:
- Protein G Purified
- Reactivities:
- Human
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -70[o]C lyophilized. Avoid freeze/thaw cycles.
- Supplier:
- ReliaTech
- Type:
- Antibody: Monoclonal Antibody