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Antibodies

Cathepsin E

Product Sizes
100 ug
£674.12
101-M248-100UG
About this Product
SKU:
101-M248
Additional Names:
CTSE; CATE
Application:
Western Blot
Buffer:
PBS
translate.label.attr.clone:
4F50
Clonality:
Monoclonal
Extra Details:
Cathepsin E is an intracellular aspartic protease of the pepsin family. Unlike Cathepsin D, another member of the same family and a lysosomal protease with relatively ubiquitous distribution, Cathepsin E is not a lysosomal enzyme and has a limited cell and tissue distribution. However, both Cathepsin D and E play an important role in the degradation of proteins, the generation of bioactive proteins, and antigen processing. Both enzymes are efficient in cleaving Swedish mutant of amyloid precursor protein (APP) at the B Beta site but show almost no reactivity with wildtype APP. Human Cathepsin E is synthesized as a precursor protein, consisting of a signal peptide (aa 1-17), a propeptide (aa 18-53), and a mature chain (aa 54-396).
Formulation:
lyophilized
Host:
Mouse
Immunogen:
recombinant human Cathepsin-E
Isotype:
IgG2
Purification:
Protein G Purified
Reactivities:
Human
Shipping Conditions:
Ambient
Storage Conditions:
-70[o]C lyophilized. Avoid freeze/thaw cycles.
Supplier:
ReliaTech
Type:
Antibody: Monoclonal Antibody