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Antibodies

VEGFR-1/Flt-1

Product Sizes
100 ug
£370.59
101-M24-100UG
About this Product
SKU:
101-M24
Additional Names:
vascular endothelial growth factor receptor-1; FLT1; VEGF receptor 1
Application:
ELISA, Immunofluorescence, Western Blot
Buffer:
PBS
translate.label.attr.clone:
EWC
Clonality:
Monoclonal
Extra Details:
VEGFR-1 is a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia.
Formulation:
lyophilized
Host:
Mouse
Immunogen:
Recombinant human soluble Flt-1 (D5)
Isotype:
IgG1
Purification:
Protein G Purified
Reactivities:
Human, Mouse
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C lyophilized. Aliquot. Avoid freeze/thaw cycles.
Supplier:
ReliaTech
Type:
Antibody: Monoclonal Antibody