ADAM-8
Product Sizes
100 ug
£674.12
101-M208-100UG
About this Product
- SKU:
- 101-M208
- Additional Names:
- ADAM8; MS2; CD156
- Application:
- Western Blot
- Buffer:
- PBS
- translate.label.attr.clone:
- 6J12
- Clonality:
- Monoclonal
- Extra Details:
- ADAM8, also known as cell surface antigen MS2 or CD156a, is a member of the ADAM family that contains a disintegrin and metalloprotease-like domain. ADAM8 can cleave a variety of substrates and has been shown as a sheddase for the low affinity IgE receptor CD23 and the neural recognition molecule CHL1. Expression and regulation studies suggest that ADAM8 is a novel osteoclast stimulating factor and may play a role in asthma. The 824 amino acid precursor of human ADAM8 consists of a signal peptide (residues 1 to 16), a pro peptide (residues 17 to 199), a metaloprotease domain (residues 200 to 400), a disintegrinlike domain (residues 408 to 494), a cysteinerich region (residues 497 to 613), an EGF-like domain (residues 614 to 640), a transmembrane region (residues 656 to 676) and a cytoplasmic domain (residues 677 to 824).
- Formulation:
- lyophilized
- Host:
- Mouse
- Immunogen:
- recombinant human ADAM-8 (extracellular domain)
- Isotype:
- IgG1
- Purification:
- Protein G Purified
- Reactivities:
- Human
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -70[o]C lyophilized. Avoid freeze/thaw cycles.
- Supplier:
- ReliaTech
- Type:
- Antibody: Monoclonal Antibody