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Antibodies

ADAM-10

Product Sizes
100 ug
£674.12
101-M205-100UG
About this Product
SKU:
101-M205
Additional Names:
ADAM10; kuz; AD10; MADM; CD156c; HsT18717
Application:
Western Blot
Buffer:
PBS
translate.label.attr.clone:
6D31
Clonality:
Monoclonal
Extra Details:
The monoclonal antibody reacts with human CD156c, which is also known as a disintegrin and metalloproteinase domain-containing protein (ADAM) 10. This type I transmembrane glycoprotein is expressed ubiquitously on hematopoietic and non-hematopoietic cell types. Studies demonstrate that CD156c expression is regulated by PAX2 in cancer cells. CD156c plays a critical role in hematopoiesis, including lymphocyte development, and autoimmunity by regulating the shedding and secretion of various receptors and chemokines, including Notch, CD23, CXCL16, and the IL-6R. Finally, deregulated CD156c expression has been associated with T-cell acute lymphoblastic lymphoma (T-ALL) and Alzheimer's disease.
Formulation:
lyophilized
Host:
Mouse
Immunogen:
recombinant human ADAM-10 (extracellular domain)
Isotype:
IgG2
Purification:
Protein G Purified
Reactivities:
Human
Shipping Conditions:
Ambient
Storage Conditions:
-70[o]C lyophilized. Avoid freeze/thaw cycles.
Supplier:
ReliaTech
Type:
Antibody: Monoclonal Antibody