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Antibodies

Eotaxin-3

Product Sizes
500 ug
£307.06
101-M19-500UG
About this Product
SKU:
101-M19
Additional Names:
CCL26; IMAC; TSC-1; MIP-4a; SCYA26; MIP-4alpha
Application:
Block/Inhibit/Neutralise, ELISA, Western Blot
Buffer:
PBS
translate.label.attr.clone:
(#4M27)
Clonality:
Monoclonal
Extra Details:
Eotaxin3, also named CCL26 or SCYA26, is a novel human CC chemokine that maps to chromosome 7q11.2, within 40 kilobases of the Eotaxin2 loci. Eotaxin3/ CCL26 has been shown to be constitutively expressed in the heart and ovary. In addition, low levels of Eotaxin3/ CCL26 expression can also be detected in various tissues. The expression of Eotaxin 3/CCL26 in vascular endothelial cells has been shown to be upregulated by IL13 and IL4. Eotaxin3/ CCL26 cDNA encodes a 94 amino acid (aa) residue protein with a putative signal peptide of either 23 or 26 aa residues. Eotaxin3/ CCL26 induces calcium flux in eosinophils as well as in CCR3transfected cells. Eotaxin 3/ CCL26 has also been shown to cross-desensitize cells to other CCR3 ligands.
Formulation:
lyophilized from PBS
Host:
Mouse
Immunogen:
Recombinant Human Eotaxin-3 (CCL26)
Isotype:
IgG1, kappa
Purification:
Protein A Purified
Reactivities:
Human
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C lyophilized. Aliquot. Avoid freeze/thaw cycles.
Supplier:
ReliaTech
Type:
Antibody: Monoclonal Antibody