CD105/Endoglin
Product Sizes
100 ug
£674.12
101-M160-100UG
About this Product
- SKU:
- 101-M160
- Additional Names:
- Endoglin; END; ORW; HHT1; ORW1; CD105
- Application:
- Immunohistochemistry
- Buffer:
- PBS
- translate.label.attr.clone:
- 12J11
- Clonality:
- Monoclonal
- Extra Details:
- CD105 or Endoglin is a Type I transmembrane protein, which is highly expressed on vascular endothelial cells. It exists on an O- and N-glycosylated homodimer. Up regulation of endoglin expression has been demonstrated in tumor vasculature and proliferating cells, suggesting that it is a proliferation associated endothelial marker. CD105 binds to TGF-B Beta1 and B Beta3 with high affinity but not to TGF-B Beta2.
- Formulation:
- lyophilized
- Host:
- Mouse
- Immunogen:
- cell membrane glycoproteins of lymphoblastic leukemia cells
- Isotype:
- IgG1
- Purification:
- Protein G/A chromatography
- Reactivities:
- Human
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -70[o]C lyophilized. Avoid freeze/thaw cycles.
- Supplier:
- ReliaTech
- Type:
- Antibody: Monoclonal Antibody