Skip to content

Basket

You currently have no items in your basket.

Total (excl. vat) £0.00
View basket & checkout
Antibodies

Arginase 1

Product Sizes
100 ug
£674.12
101-M136-100UG
About this Product
SKU:
101-M136
Additional Names:
Liver-type arginase, Type I arginase, ARG1
Application:
Flow Cytometry, Immunoprecipitation, Western Blot
Buffer:
PBS
translate.label.attr.clone:
41P23
Clonality:
Monoclonal
Extra Details:
Arginase-1 (ARG1) deficiency is a rare autosomal recessive disorder that affects the liver-based urea cycle, leading to impaired ureagenesis. This genetic disorder is caused by 40+ mutations found fairly uniformly spread throughout the ARG1 gene, resulting in partial or complete loss of enzyme function, which catalyzes the hydrolysis of arginine to ornithine and urea. ARG1-deficient patients exhibit hyperargininemia with spastic paraparesis, progressive neurological and intellectual impairment, persistent growth retardation, and infrequent episodes of hyperammonemia, a clinical pattern that differs strikingly from other urea cycle disorders.
Formulation:
lyophilized
Host:
Mouse
Immunogen:
Recombinant human Arginase 1
Isotype:
IgG2
Purification:
Protein G Purified
Reactivities:
Human
Shipping Conditions:
Ambient
Storage Conditions:
-70[o]C lyophilized. Avoid freeze/thaw cycles.
Supplier:
ReliaTech
Type:
Antibody: Monoclonal Antibody