MMP-12
Product Sizes
100 ug
£674.12
101-M114-100UG
About this Product
- SKU:
- 101-M114
- Additional Names:
- MMP12; ME; HME; MME; MMP-12
- Application:
- IHC-Paraffin, Western Blot
- Buffer:
- PBS
- translate.label.attr.clone:
- 7G20
- Clonality:
- Monoclonal
- Extra Details:
- MMP12, also known as macrophage elastase, is a zinc and calcium dependent endopeptidase expressed constitutively in macrophages and can be induced in monocytes. MMP12 can degrade a broad spectrum of substrates, including type IV collagen, fibronectin, laminin, vitronectin, proteoglycans, chondroitin sulfate, myelin basic protein, A Alpha-1antitrypsin, and plasminogen. It can also activate MMP2 and MMP-3. The MMP12 precursor consists of a pro domain, a catalytic domain containing the zinc-binding site, and a C-terminal hemopexin like domain.
- Formulation:
- lyophilized
- Host:
- Mouse
- Immunogen:
- recombinant human MMP-12
- Isotype:
- IgG2
- Purification:
- Protein G Purified
- Reactivities:
- Human
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C lyophilized. Avoid freeze/thaw cycles.
- Supplier:
- ReliaTech
- Type:
- Antibody: Monoclonal Antibody