Eotaxin-2
Product Sizes
500 ug
£307.06
101-M01-500UG
About this Product
- SKU:
- 101-M01
- Additional Names:
- CCL24; Ckb-6; MPIF2; MPIF-2; SCYA24
- Application:
- ELISA, IHC-Paraffin, Western Blot
- Buffer:
- PBS
- Clonality:
- Monoclonal
- Extra Details:
- Eotaxin2, also named MPIF-2 and CkB Beta6, is a CC chemokine that is designated CCL24. Eotaxin2 cDNA encodes a 10.5 kDa, 119 amino acid residue precursor protein with a 26 aa residue signal peptide that is cleaved to generate a mature protein predicted to contain 93 amino acid residues with an N-glycosylation site. C-terminally truncated variants with 78, 73, 75 and 76 residues have also been described. Eotaxin 2 shares 40%, 42% and 39% amino acid sequence identity with other CC chemokines CCL7/MCP3, CCL3/MIP1A Alpha, and CCL11/Eotaxin, respectively. Eotaxin2 mRNA is weakly expressed in activated monocytes and T lymphocytes. Recombinant Eotaxin2 induces chemotaxis of eosinophils, basophils, and resting T lymphocytes, but not monocytes or activated T lymphocytes. Eotaxin2 also suppresses colony formation by high proliferative multipotential hematopoietic progenitors. On eosinophils, the effects of Eotaxin2, Eotaxin and CCL13/MCP4 are mediated by the receptor CCR3.
- Formulation:
- lyophilized from PBS
- Host:
- Mouse
- Immunogen:
- Recombinant Human Eotaxin-2 (CCL24)
- Isotype:
- IgG1, kappa
- Purification:
- Protein A Purified
- Reactivities:
- Human
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C lyophilized. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- ReliaTech
- Type:
- Antibody: Monoclonal Antibody