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Proteins and Peptides

GDF-5 (BMP-14/CDMP-1)

Product Sizes
GDF-5 (BMP-14/CDMP-1)
£ POA
100-389-L250
About this Product
SKU:
100-389-L250
Additional Names:
GDF5; OS5; LAP4; BMP14; CDMP1; SYNS2
Extra Details:
GDF-5 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Mutations in this gene are associated with acromesomelic dysplasia, Hunter-Thompson type; brachydactyly, type C; and chondrodysplasia, Grebe type. These associations confirm that the gene product plays a role in skeletal development. GDF-5 produced in E.Coli is a homodimer, non-glycosylated, polypeptide chain containing 2 x 120 amino acids and having a total molecular mass of 26.8 Dalton.
Formulation:
lyophilized
Molecular Weight:
26.8 kDa
Purity:
> 98% by SDS-PAGE & RP-HPLC
Reactivities:
Human
Sequence:
APLATRQGKR PSKNLKARCS RKALHVNFKD MGWDDWIIAP LEYEAFHCEG LCEFPLRSHL EPTNHAVIQT LMNSMDPEST PPTCCVPTRL SPISILFIDS ANNVVYKQYE DMVVESCGCR
Shipping Conditions:
Blue Ice
Supplier:
ReliaTech
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
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