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Proteins and Peptides

GLP-1

Product Sizes
200 ug
£178.82
100-339-200UG
1000 ug
£307.06
100-339-1000UG
About this Product
SKU:
100-339
Additional Names:
GLP1; GLP2; GRPP
Extra Details:
GLP-1 is a proglucagon-derived peptide hormone secreted primarily by intestinal L cells during feeding. Its major physiological function is stimulation of pancreatic B Beta-cells to release appropriate amounts of insulin after glucose absorption. Other biological actions exhibited by GLP-1 include suppression of plasma glucagons levels, inhibition of gastric motility, and promotion of satiety. The secretion of GLP-1 from intestinal L cells is stimulated by nutrients, hormones, and neural inputs. On the other hand, insulin has been reported to inhibit GLP-1 release, indicating that a feedback loop mechanism regulates GLP-1 secretion. In addition to being the precursor of GLP-1, proglucagon, whose primary structure is highly conserved in mammalian species, is also the precursor for other members of the glucagon family of peptide hormones including glicentin-related pancreatic peptide (GRPP), glucagons, and GLP-2. Recombinant human GLP-1 is a 3.3 kDa consisting of 31 amino acid residues.
Formulation:
lyophilized
Host:
Rabbit
Molecular Weight:
3.3 kDa
Purity:
> 98% by SDS-PAGE & HPLC analyses
Reactivities:
Human
Sequence:
HAEGTFTSDV SSYLEGQAAK EFIAWLVKGR G
Shipping Conditions:
Ambient
Storage Conditions:
Room Temperature
Supplier:
ReliaTech
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins