BD-4
Product Sizes
5 ug
£178.82
100-331-5UG
20 ug
£307.06
100-331-20UG
About this Product
- SKU:
- 100-331
- Additional Names:
- DEFB104A; BD-4; DEFB4; hBD-4; DEFB-4; DEFB104; DEFB104B
- translate.label.attr.clone:
- (#6M23)
- Extra Details:
- Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The A Alpha-defensins are distinguished from the B Beta-defensins by the pairing of their three disulfide bonds. To date, four human B Beta-defensins have been identified; BD-1, BD-2, BD-3 and BD-4. The B Beta-defensin proteins are expressed as the C-terminal portion of precursors and are released by proteolytic cleavage of a signal sequence. B Beta-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds. B Beta-defensins are 3-5 kDa peptides ranging in size from 33-47 amino acid residues. BD-4 is expressed in testis, stomach, uterus, neutrophils, thyroid, lung and kidney. In addition to its direct antimicrobial activities, BD-4 is chemo attractant towards human blood monocytes. Recombinant human BD-4 is a 6.0 kDa protein containing 50 amino acid residues.
- Formulation:
- lyophilized
- Host:
- Mouse
- Molecular Weight:
- 6.0 kDa
- Purity:
- 98% by SDS-PAGE & HPLC analyses
- Reactivities:
- Human
- Sequence:
- EFELDRICGY GTARCRKKCR SQEYRIGRCP NTYACCLRKW DESLLNRTKP
- Shipping Conditions:
- Ambient
- Storage Conditions:
- Room Temperature
- Supplier:
- ReliaTech
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins