TNF-beta
Product Sizes
5 ug
£178.82
100-108-5UG
20 ug
£307.06
100-108-20UG
About this Product
- SKU:
- 100-108
- Additional Names:
- LTA; LT; TNFB; TNFSF1
- Extra Details:
- TNF-B Beta is a potent mediator of inflammatory and immune responses. It belongs to the TNF family of ligands and signals through TNFR1 and TNFR2. TNF-B Beta is produced by activated T and B lymphocytes, and has similar activities to TNF-A Alpha. Like TNF-A Alpha, TNF-B Beta is involved in the regulation of various biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, coagulation, and neurotransmission. TNF-B Beta is secreted as a soluble polypeptide, but can form heterotrimers with lymphotoxin-B Beta, which effectively anchors the TNF-B Beta to the cell surface. TNF-B Beta is cytotoxic to a wide range of tumor cells. Recombinant human TNF-B Beta is a secreted 171 amino acid protein (18.6 kDa) which forms an active non-disulfide linked homotrimer structure in solution.
- Formulation:
- lyophilized
- Molecular Weight:
- 18.6 kDa
- Purity:
- > 98% by SDS-PAGE & HPLC analyses
- Reactivities:
- Human, Mouse
- Sequence:
- MLPGVGLTPS AAQTARQHPK MHLAHSTLKP AAHLIGDPSK QNSLLWRANT DRAFLQDGFS LSNNSLLVPT SGIYFVYSQV VFSGKAYSPK ATSSPLYLAH EVQLFSSQYP FHVPLLSSQK MVYPGLQEPW LHSMYHGAAF QLTQGDQLST HTDGIPHLVL SPSTVFFGAF AL
- Shipping Conditions:
- Ambient
- Storage Conditions:
- Room Temperature
- Supplier:
- ReliaTech
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins