LIGHT
Product Sizes
3 ug
£178.82
100-106-3UG
15 ug
£307.06
100-106-15UG
About this Product
- SKU:
- 100-106
- Additional Names:
- TNFSF14, HVEM-L, LIGHT; tumor necrosis factor (ligand) superfamily, member 14
- translate.label.attr.clone:
- (#9H11)
- Extra Details:
- LIGHT belongs to the TNF family of ligands, and can signal through the herpes virus entry mediator type A receptor (HVEM, TNFRSF14), LTB BetaR, or bind to a decoy receptor, DcR3. It is expressed in splenocytes, activated PBL, CD+8 tumor infiltrating lymphocytes, granulocytes, and monocytes. LIGHT has the ability to active NFkB, to co-stimulate the activation of lymphocytes and to induce apoptosis in certain human tumor cells. Recombinant human LIGHT has a calculated mass of 19.3 kDa containing 177 amino acid residues. Due to glycosylation LIGHT migrates between 20.0-22.5 kDa by SDS-PAGE under non-reducing conditions.
- Formulation:
- lyophilized
- Host:
- Mouse
- Immunogen:
- EC domain
- Molecular Weight:
- 19.3 kDa
- Purity:
- > 95% by SDS-PAGE & HPLC analyses
- Reactivities:
- Human
- Sequence:
- RLGEMVTRLP DGPAGSWEQL IQERRSHEVN PAAHLTGANS SLTGSGGPLL WETQLGLAFL RGLSYHDGAL VVTKAGYYYI YSKVQLGGVG CPLGLASTIT HGLYKRTPRY PEELELLVSQ QSPCGRATSS SRVWWDSSFL GGVVHLEAGE KVVVRVLDER LVRLRDGTRS YFGAFMV
- Shipping Conditions:
- Ambient
- Storage Conditions:
- Room Temperature
- Supplier:
- ReliaTech
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins