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Proteins and Peptides

IL-36 gamma (IL-1F9)

Product Sizes
2 ug
£178.82
100-092-2UG
10 ug
£307.06
100-092-10UG
About this Product
SKU:
100-092
Additional Names:
IL1E; IL1F9; IL1H1; IL-1F9; IL-1H1; IL1RP2; IL-1RP2
translate.label.attr.clone:
(#9D8)
Extra Details:
The IL-1 family is comprised of 11 structurally related ligands, including recently re-named IL-36 A Alpha (IL-1F6), B Beta (IL-1F8) and G Gamma (IL-1F9). IL-36G Gamma is highly expressed in psoriatic plaques and in tissues containing epithelial cells. IL-36G Gamma signals through the IL-1Rrp2 (IL-1R6) receptor, which is primarily expressed on certain dendritic cells. The interaction of the IL-1Rrp2 receptor with IL-36 ligands induces dendritic cell maturation and activation. IL-36G Gamma also functions as an agonist of NF-kappaB, and can stimulate the inflammatory response in bronchial epithelial cells. Recombinant human IL-36G Gamma is a 17.0 kDa protein containing 152 amino acid residues.
Formulation:
lyophilized
Host:
Rabbit
Molecular Weight:
17 kDa
Purity:
> 95% by SDS-PAGE & HPLC analyses
Reactivities:
Human
Sequence:
SMCKPITGTI NDLNQQVWTL QGQNLVAVPR SDSVTPVTVA VITCKYPEAL EQGRGDPIYL GIQNPEMCLY CEKVGEQPTL QLKEQKIMDL YGQPEPVKPF LFYRAKTGRT STLESVAFPD WFIASSKRDQ PIILTSELGK SYNTAFELNI ND
Shipping Conditions:
Ambient
Storage Conditions:
Room Temperature
Supplier:
ReliaTech
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins