IL-36 beta (IL-1F8)
Product Sizes
2 ug
£178.82
100-091-2UG
10 ug
£307.06
100-091-10UG
About this Product
- SKU:
- 100-091
- Additional Names:
- FIL1; FIL1H; IL1F8; IL1H2; IL-1F8; IL-1H2; IL1-ETA; FIL1-(ETA); FILI-(ETA)
- translate.label.attr.clone:
- Rabbit IgG
- Extra Details:
- The IL-1 family is comprised of 11 structurally related ligands, including recently re-named IL-36A Alpha (IL-1F6), B Beta (IL-1F8) and G Gamma (IL-1F9). IL-36B Beta is highly expressed in psoriatic plaques, and at lower levels in various other tissues. IL-36B Beta signals through the IL-1Rrp2 (IL-1R6) receptor, which is primarily expressed on certain dendritic cells. The interaction of the IL-1Rrp2 receptor with IL-36 ligands induces dendritic cell maturation and activation. IL-36B Beta also functions as an agonist of NF-kappaB, and stimulates the production of pro-inflammatory proteins, including IL-6, IL-8, BD-2, and BD-3. Recombinant human IL-36B Beta is a 17.3 kDa protein containing 154 amino acid residues.
- Formulation:
- lyophilized
- Host:
- E. coli
- Molecular Weight:
- 17.3 kDa
- Purity:
- > 98% by SDS-PAGE & HPLC analyses
- Reactivities:
- Human
- Sequence:
- MREAAPKSYA IRDSRQMVWV LSGNSLIAAP LSRSIKPVTL HLIACRDTEF SDKEKGNMVY LGIKGKDLCL FCAEIQGKPT LQLKEKNIMD LYVEKKAQKP FLFFHNKEGS TSVFQSVSYP GWFIATSTTS GQPIFLTKER GITNNTNFYL DSVE
- Shipping Conditions:
- Ambient
- Storage Conditions:
- Room Temperature
- Supplier:
- ReliaTech
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins