Neurturin
Product Sizes
5 ug
£178.82
100-083-5UG
20 ug
£307.06
100-083-20UG
About this Product
- SKU:
- 100-083
- Additional Names:
- NRTN; NTN
- translate.label.attr.clone:
- (#9F42)
- Extra Details:
- Neurturin is a disulfide-linked homodimer neurotrophic factor structurally related to GDNF, Artemin, and Persephin. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. Neurturin signals through a multicomponent receptor system, composed of RET and one of four GFR A Alpha (A Alpha1-A Alpha4) receptors. Neurturin promotes the development and survival of sympathetic and sensory neurons by signaling through a receptor system composed of RET and GFRA Alpha2. The functional form of human Neurturin is a disulfide-linked homodimer, of two 11.8 kDa polypeptide monomers (204 total amino acid residues). Each monomer contains seven conserved cysteine residues, one of which (Cys 69) is used for inter-chain disulfide bridging and the others are involved in intramolecular ring formation known as the cysteine knot configuration.
- Formulation:
- lyophilized
- Host:
- Mouse
- Molecular Weight:
- 11.8 kDa
- Purity:
- > 98% by SDS-PAGE & HPLC analysis
- Reactivities:
- Human, Mouse, Rat
- Sequence:
- ARLGARPCGL RELEVRVSEL GLGYASDETV LFRYCAGACE AAARVYDLGL RRLRQRRRLR RERVRAQPCC RPTAYEDEVS FLDAHSRYHT VHELSARECA CV
- Shipping Conditions:
- Ambient
- Storage Conditions:
- Room Temperature
- Supplier:
- ReliaTech
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins