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Proteins and Peptides

BDNF

Product Sizes
2 ug
£178.82
100-005-2UG
10 ug
£307.06
100-005-10UG
About this Product
SKU:
100-005
Additional Names:
BDNF
translate.label.attr.clone:
(#7C39)
Extra Details:
BDNF is a member of the NGF family of neurotrophic growth factors. Like other members of this family, BDNF supports neuron proliferation and survival. BDNF can bind to a low affinity cell surface receptor called LNGFR, which also binds other neurotrophins such as NGF, NT-3 and NT-4. However, BDNF mediates its neurotrophic properties by signaling through a high affinity cell surface receptor called gp145/trkB. BDNF is expressed as the C-terminal portion of a 247 amino acid polypeptide precursor, which also contains a signal sequence of 18 amino acid residues and a propeptide of 110 amino acid residues. Recombinant Human BDNF is a 27.0 kDa homodimer of two 120 amino acid subunits linked by strong non-covalent interactions. Human and Mouse BDNF sequences are identical.
Formulation:
lyophilized
Host:
Rabbit
Molecular Weight:
27.0 kDa
Purity:
> 98% by SDS-PAGE & HPLC analyses
Reactivities:
Amphibian, Avian, Guinea Pig, Hamster, Human, Mouse, Non-human Primate, Rat
Sequence:
MHSDPARRGE LSVCDSISEW VTAADKKTAV DMSGGTVTVL EKVPVSKGQL KQYFYETKCN PMGYTKEGCR GIDKRHWNSQ CRTTQSYVRA LTMDSKKRIG WRFIRIDTSC VCTLTIKRGR
Shipping Conditions:
Ambient
Storage Conditions:
Room Temperature
Supplier:
ReliaTech
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins