BDNF
Product Sizes
2 ug
£178.82
100-005-2UG
10 ug
£307.06
100-005-10UG
About this Product
- SKU:
- 100-005
- Additional Names:
- BDNF
- translate.label.attr.clone:
- (#7C39)
- Extra Details:
- BDNF is a member of the NGF family of neurotrophic growth factors. Like other members of this family, BDNF supports neuron proliferation and survival. BDNF can bind to a low affinity cell surface receptor called LNGFR, which also binds other neurotrophins such as NGF, NT-3 and NT-4. However, BDNF mediates its neurotrophic properties by signaling through a high affinity cell surface receptor called gp145/trkB. BDNF is expressed as the C-terminal portion of a 247 amino acid polypeptide precursor, which also contains a signal sequence of 18 amino acid residues and a propeptide of 110 amino acid residues. Recombinant Human BDNF is a 27.0 kDa homodimer of two 120 amino acid subunits linked by strong non-covalent interactions. Human and Mouse BDNF sequences are identical.
- Formulation:
- lyophilized
- Host:
- Rabbit
- Molecular Weight:
- 27.0 kDa
- Purity:
- > 98% by SDS-PAGE & HPLC analyses
- Reactivities:
- Amphibian, Avian, Guinea Pig, Hamster, Human, Mouse, Non-human Primate, Rat
- Sequence:
- MHSDPARRGE LSVCDSISEW VTAADKKTAV DMSGGTVTVL EKVPVSKGQL KQYFYETKCN PMGYTKEGCR GIDKRHWNSQ CRTTQSYVRA LTMDSKKRIG WRFIRIDTSC VCTLTIKRGR
- Shipping Conditions:
- Ambient
- Storage Conditions:
- Room Temperature
- Supplier:
- ReliaTech
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins