TOP1 Rabbit monoclonal antibody
Product Sizes
100 ul
£362.00
RDSA66922-100UL
About this Product
- SKU:
- RDSA66922
- Additional Names:
- DNA topoisomerase 1;DNA topoisomerase I;TOP1;TOPI;topoisomerase I;type I DNA
- Application:
- Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
- Buffer:
- Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Clonality:
- Monoclonal
- Extra Details:
- Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand.|This is a TOP1 Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.
- Host:
- Rabbit
- Immunogen:
- A synthesized peptide derived from human TOP1
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Reddot
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:top1-rabbit-mab-50374.html
