APC Rabbit monoclonal antibody
Product Sizes
100 ul
£362.00
RDSA66852-100UL
About this Product
- SKU:
- RDSA66852
- Additional Names:
- APC;APC protein;Adenomatous polyposis coli protein;DP2.5;mAPC
- Application:
- Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
- Buffer:
- Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Clonality:
- Monoclonal
- Extra Details:
- This is a APC Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.|Tumor suppressor. Promotes rapid degradation of CTNNB1 and participates in Wnt signaling as a negative regulator. APC activity is correlated with its phosphorylation state. Activates the GEF activity of SPATA13 and ARHGEF4. Plays a role in hepatocyte growth factor (HGF)-induced cell migration. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Acts as a mediator of ERBB2-dependent stabilization of microtubules at the cell cortex.
- Host:
- Rabbit
- Immunogen:
- A synthesized peptide derived from human APC
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Reddot
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:apc-rabbit-mab-50304.html
