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Antibodies

Caspase-8 Rabbit monoclonal antibody

Product Sizes
100 ul
£362.00
RDSA66809-100UL
About this Product
SKU:
RDSA66809
Additional Names:
CASP8;ALPS2B;Apoptotic protease Mch-5;Apoptotic cysteine protease;Casp-8;Caspase-8;CAP4;Caspase 8;MACH;MCH5;Pro Caspase 8;FADD-like ICE;FLICE
Application:
Western Blot
Buffer:
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Clonality:
Monoclonal
Extra Details:
Apoptosis induced through the CD95 receptor (Fas/APO-1) and tumor necrosis factor receptor 1 (TNFR1) activates caspase-8 and leads to the release of the caspase-8 active fragments, p18 and p10 (1-3). Activated caspase-8 cleaves and activates downstream effector caspases such as caspase-1, -3, -6, and -7. Caspase-3 ultimately elicits the morphological hallmarks of apoptosis, including DNA fragmentation and cell shrinkage.|This is a Caspase-8 Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.
Host:
Rabbit
Immunogen:
A synthesized peptide derived from human Caspase-8
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Reddot
Type:
Antibody: Monoclonal Antibody