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Antibodies

SATB1 Rabbit monoclonal antibody

Product Sizes
100 ul
£362.00
RDSA66501-100UL
About this Product
SKU:
RDSA66501
Additional Names:
DNA binding protein SATB1;DNA-binding protein SATB1;SATB homeobox 1
Application:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
Buffer:
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Clonality:
Monoclonal
Extra Details:
SATB1 is a crucial silencing factor contributing to the initiation of X inactivation mediated by Xist RNA that occurs during embryogenesis and in lymphoma (By similarity). Binds to DNA at special AT-rich sequences, the consensus SATB1-binding sequence (CSBS), at nuclear matrix- or scaffold-associated regions. Thought to recognize the sugar-phosphate structure of double-stranded DNA. Transcriptional repressor controlling nuclear and viral gene expression in a phosphorylated and acetylated status-dependent manner, by binding to matrix attachment regions (MARs) of DNA and inducing a local chromatin-loop remodeling.|This is a SATB1 Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.
Host:
Rabbit
Immunogen:
A synthesized peptide derived from human SATB1
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Reddot
Type:
Antibody: Monoclonal Antibody