LRRK2 Rabbit monoclonal antibody
Product Sizes
100 ul
£362.00
RDSA65270-100UL
About this Product
- SKU:
- RDSA65270
- Additional Names:
- Leucine-rich repeat serine/threonine-protein kinase 2;Dardarin;PARK8;ROCO2;RIPK7;LRRK2
- Application:
- Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
- Buffer:
- Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Clonality:
- Monoclonal
- Extra Details:
- LRRK2 positively regulates autophagy through a calcium-dependent activation of the CaMKK/AMPK signaling pathway. The process involves activation of nicotinic acid adenine dinucleotide phosphate (NAADP) receptors, increase in lysosomal pH, and calcium release from lysosomes. Together with RAB29, plays a role in the retrograde trafficking pathway for recycling proteins, such as mannose 6 phosphate receptor (M6PR), between lysosomes and the Golgi apparatus in a retromer-dependent manner.|This is a LRRK2 Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.
- Host:
- Rabbit
- Immunogen:
- A synthesized peptide derived from human LRRK2
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Reddot
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:lrrk2-rabbit-mab-48744.html
