Cyclin E1 (Phospho-Thr77) Rabbit monoclonal antibody
Product Sizes
100 ul
£362.00
RDSA65141-100UL
About this Product
- SKU:
- RDSA65141
- Additional Names:
- CCNE;Ccne1;cyclin E variant ex5del;cyclin E variant ex7del;Cyclin E1;Cyclin Es;Cyclin Et;G1/S specific cyclin E;G1/S-specific cyclin-E1
- Application:
- Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
- Buffer:
- Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Clonality:
- Monoclonal
- Extra Details:
- Cyclin E1 and cyclin E2 can associate with and activate CDK2. Upon DNA damage, upregulation/activation of the CDK inhibitors p21 Waf1/Cip1 and p27 Kip1 prevent cyclin E/CDK2 activation, resulting in G1/S arrest. Cyclin E1 is phosphorylated at multiple sites in vivo including Thr62, Ser88, Ser72, Thr380 and Ser384, and is controlled by at least two kinases, CDK2 and GSK-3.|This is a Cyclin E1 (Phospho-Thr77) Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.
- Host:
- Rabbit
- Immunogen:
- A synthesized peptide derived from human Cyclin E1
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Reddot
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:cyclin-e1-phospho-thr77-rabbit-mab-48615.html
