CrkII (Tyr221) Rabbit monoclonal antibody
Product Sizes
100 ul
£362.00
RDSA65130-100UL
About this Product
- SKU:
- RDSA65130
- Additional Names:
- Adapter molecule crk;avian sarcoma virus CT10 (v-crk) oncogene homolog;CRK;CRKII;Proto-oncogene c-Crk
- Application:
- Immunocytochemistry, Immunofluorescence, Western Blot
- Buffer:
- Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Clonality:
- Monoclonal
- Extra Details:
- The Crk-I and Crk-II forms differ in their biological activities. Crk-II has less transforming activity than Crk-I. Crk-II mediates attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. Involved in phagocytosis of apoptotic cells and cell motility via its interaction with DOCK1 and DOCK4. May regulate the EFNA5-EPHA3 signaling.|This is a CrkII (Tyr221) Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.
- Host:
- Rabbit
- Immunogen:
- A synthesized peptide derived from human Phospho-CrkII (Tyr221)
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Reddot
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:crkii-tyr221-rabbit-mab-48604.html
