p53 (Phospho-Ser376) Rabbit monoclonal antibody
Product Sizes
100 ul
£362.00
RDSA65101-100UL
About this Product
- SKU:
- RDSA65101
- Additional Names:
- Antigen NY-CO-13;Cellular tumor antigen p53;Phosphoprotein p53;TP53;Tumor suppressor p53
- Application:
- Western Blot
- Buffer:
- Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Clonality:
- Monoclonal
- Extra Details:
- Plays an essential role in the regulation of cell cycle, specifically in the transition from G0 to G1. It is found in very low levels in normal cells, however, in a variety of transformed cell lines, it is expressed in high amounts, and believed to contribute to transformation and malignancy. p53 is a DNA-binding protein containing DNA-binding, oligomerization and transcription activation domains. It is postulated to bind as a tetramer to a p53-binding site and activate expression of downstream genes that inhibit growth and/or invasion, and thus function as a tumor suppressor.|This is a p53 (Phospho-Ser376) Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.
- Host:
- Rabbit
- Immunogen:
- A synthesized peptide derived from human Phospho-p53 (S376)
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Reddot
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:p53-phospho-ser376-rabbit-mab-48575.html
