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Antibodies

EPHA2/5 (Phospho-Tyr594) Antibody

Product Sizes
100 ul
£372.00
RDSA62475-100UL
About this Product
SKU:
RDSA62475
Additional Names:
ARCC2;ECK;EPHA2
Application:
Western Blot
Buffer:
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Activated by the ligand ephrin-A1/EFNA1 regulates migration, integrin-mediated adhesion, proliferation and differentiation of cells. Regulates cell adhesion and differentiation through DSG1/desmoglein-1 and inhibition of the ERK1/ERK2 (MAPK3/MAPK1, respectively) signaling pathway.|This is a EPHA2/5 (Phospho-Tyr594) Phospho-Specific Antibody from Reddot Biotech. This product is for Research Use Only.
Host:
Rabbit
Immunogen:
Peptide sequence around phosphorylation site of tyrosine 594 (H-T-Y(p)-E-D) derived from Human EPHA2/5.
Isotype:
IgG
Molecular Weight:
110kDa
Purification:
Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Reddot
Type:
Antibody: Polyclonal Antibody