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Antibodies

BLK (Phospho-Tyr501) Antibody

Product Sizes
100 ul
£372.00
RDSA62415-100UL
About this Product
SKU:
RDSA62415
Additional Names:
p55-BLK;EC 2.7.10.2;kinase Blk;B lymphocyte kinase;Tyrosine-protein kinase BLK
Application:
Immunohistochemistry
Buffer:
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
Non-receptor tyrosine kinase involved in B-lymphocyte development, differentiation and signaling. B-cell receptor (BCR) signaling requires a tight regulation of several protein tyrosine kinases and phosphatases, and associated coreceptors. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activation. Signaling through BLK plays an important role in transmitting signals through surface immunoglobulins and supports the pro-B to pre-B transition, as well as the signaling for growth arrest and apoptosis downstream of B-cell receptor.|This is a BLK (Phospho-Tyr501) Phospho-Specific Antibody from Reddot Biotech. This product is for Research Use Only.
Host:
Rabbit
Immunogen:
Peptide sequence around phosphorylation site of tyrosine 501 (R-Q-Y(p)-E-L) derived from Human BLK.
Isotype:
IgG
Molecular Weight:
57kda
Purification:
Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Reddot
Type:
Antibody: Polyclonal Antibody