Bub3 (Phospho-Tyr207) Antibody
Product Sizes
100 ul
£372.00
RDSA62353-100UL
About this Product
- SKU:
- RDSA62353
- Additional Names:
- Mitotic checkpoint protein BUB3;Hbub3;BUB3L;BUB3 budding uninhibited by benzimidazoles 3 homolog;budding uninhibited by benomyl
- Application:
- Western Blot
- Buffer:
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Has a dual function in spindle-assembly checkpoint signaling and in promoting the establishment of correct kinetochore-microtubule (K-MT) attachments. Promotes the formation of stable end-on bipolar attachments. Necessary for kinetochore localization of BUB1. Regulates chromosome segregation during oocyte meiosis. The BUB1/BUB3 complex plays a role in the inhibition of anaphase-promoting complex or cyclosome (APC/C) when spindle-assembly checkpoint is activated and inhibits the ubiquitin ligase activity of APC/C by phosphorylating its activator CDC20. This complex can also phosphorylate MAD1L1.|This is a Bub3 (Phospho-Tyr207) Phospho-Specific Antibody from Reddot Biotech. This product is for Research Use Only.
- Host:
- Rabbit
- Immunogen:
- Peptide sequence around phosphorylation site of Tyrosine 207 (V-E-Y(p)-L-D) derived from Human Bub3.
- Isotype:
- IgG
- Molecular Weight:
- 40kda
- Purification:
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Reddot
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:bub3-phospho-tyr207-antibody-48390.html
