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Antibodies

p53(Phospho-Ser33) Antibody

Product Sizes
100 ul
£372.00
RDSA62099-100UL
About this Product
SKU:
RDSA62099
Additional Names:
Antigen NY-CO-13 Phosphoprotein p53 Tumor suppressor p53; Cellular tumor antigen p53; TP53
Application:
Immunofluorescence, Western Blot
Buffer:
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
Acts as a tumor suppressor in many tumor types;induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Implicated in Notch signaling cross-over.|This is a p53(Phospho-Ser33) Phospho-Specific Antibody from Reddot Biotech. This product is for Research Use Only.
Host:
Rabbit
Immunogen:
Peptide sequence around phosphorylation site of serine 33 (V-L-S(p)-P-L) derived from Human p53.
Isotype:
IgG
Purification:
Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Reddot
Type:
Antibody: Polyclonal Antibody