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Antibodies

Smad2 Monoclonal Antibody

Product Sizes
100 ul
£362.00
RDSA55167-100UL
About this Product
SKU:
RDSA55167
Additional Names:
hMAD 2;hMAD-2;hSMAD2;JV18 1;JV18;JV18;JV18-1;JV181;MAD;MAD;MAD homolog 2;MAD Related Protein 2;Mad-related protein 2;MADH2;MADR2;MGC22139;MGC34440;Mothers Against Decapentaplegic Homolog 2;Mothers Against Decapentaplegic Homolog 2
Application:
Immunocytochemistry, Western Blot
Clonality:
Monoclonal
Extra Details:
Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases.Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and,on formation of the SMAD2/SMAD4 complex,activates transcription.May act as a tumor suppressor in colorectal carcinoma.Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.|This is a Smad2 Monoclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Host:
Mouse
Immunogen:
Purified recombinant human SMAD2 protein fragments expressed in E.coli.
Isotype:
IgG1
Molecular Weight:
60kDa
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Reddot
Type:
Antibody: Monoclonal Antibody