TORC1 Monoclonal Antibody
Product Sizes
100 ul
£362.00
RDSA55157-100UL
About this Product
- SKU:
- RDSA55157
- Additional Names:
- KIAA0616;CREB regulated transcription coactivator 1;CREB-regulated transcription coactivator 1;CRTC1;CRTC1_HUMAN;FLJ14027;KIAA0616;MECT 1;Mucoepidermoid carcinoma translocated 1;Mucoepidermoid carcinoma translocated protein 1;TORC-1;TORC1
- Application:
- Immunocytochemistry, Western Blot
- Clonality:
- Monoclonal
- Extra Details:
- This is a TORC1 Monoclonal Antibody from Reddot Biotech. This product is for Research Use Only.|Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites.Acts as a coactivator, in the SIK/TORC signaling pathway,being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation.Enhances the interaction of CREB1 with TAF4.Regulates the expression of specific CREB-activated genes such as the steroidogenic gene,StAR.Potent coactivator of PGC1alpha and inducer of mitochondrial biogenesis in muscle cells.Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR).In the hippocampus, involved in late-phase long-term potentiation (L-LTP) maintenance at the Schaffer collateral-CA1 synapses.May be required for dendritic growth of developing cortical neurons.
- Host:
- Mouse
- Immunogen:
- Purified recombinant human CRTC1 protein fragments expressed in E.coli.
- Isotype:
- IgM
- Molecular Weight:
- 78kDa
- Reactivities:
- Human, Mouse, Non-human Primate, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Reddot
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:torc1-monoclonal-antibody-48060.html
