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Antibodies

SARS-CoV-2 NSP1 Polyclonal Antibody(2019-nCoV)

Product Sizes
50 ul
£386.00
RD90434A-50UL
100 ul
£607.00
RD90434A-100UL
About this Product
SKU:
RD90434A
Additional Names:
ORF1a polyprotein,Non-structural protein 1,Leader protein,Replicase polyprotein 1a
Application:
ELISA
Buffer:
PBS
Clonality:
Polyclonal
Concentration:
0.55 mg/ml
Extra Details:
The Severe Acute Respiratory Syndrome (SARS) Coronavirus (CoV) is an enveloped, positive-stranded RNA viruses that can cause a severe respiratory disease. Its genome consists of a 30 kb linear, non-segmented, capped, polycistronic, polyadenylated RNA molecule, the first two-third of which is directly translated into two large polyproteins. These two polypeptides are processed into 16 non-structural proteins (nsps), forming the replicase complex, which is active in the cytoplasm in close association with cellular membranes. Nsp1 was proved to be able to suppress host gene expression by promoting host mRNA degradation and was involved in cellular chemokine deregulation. This virus evades the host innate immune response in part through the expression of its non-structural protein (nsp) 1, which inhibits both host gene expression and virus- and interferon (IFN)-dependent signaling. Thus, nsp1 is a promising target for drugs, as inhibition of nsp1 would make SARS-CoV more susceptible to the host antiviral defenses.|This is a SARS-CoV-2 NSP1 (2019-nCoV) Virus Antibody from Reddot Biotech. This product is for Research Use Only.
Host:
Rabbit
Immunogen:
Recombinant SARS-CoV-2 NSP1
Isotype:
IgG
Purification:
Produced in rabbits immunized with purified,Recombinant SARS-CoV-2 NSP1
Reactivities:
Virus
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Reddot
Type:
Antibody: Polyclonal Antibody