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Antibodies

Cyclin D1 Polyclonal Antibody

Product Sizes
60 ul
£319.00
RD90376A-60UL
120 ul
£479.00
RD90376A-120UL
200 ul
£761.00
RD90376A-200UL
About this Product
SKU:
RD90376A
Additional Names:
BCL1,D11S287E,PRAD1,U21B31,CCND1,Cyclin D1,cyclin D1
Application:
Western Blot
Buffer:
PBS
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb. Mutations, amplification and overexpression of this gene, which alters cell cycle progression, are observed frequently in a variety of tumors and may contribute to tumorigenesis.|This is a Cyclin D1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Host:
Rabbit
Immunogen:
A synthetic peptide of human Cyclin D1
Isotype:
IgG
Molecular Weight:
75KDa/100KDa
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Reddot
Type:
Antibody: Polyclonal Antibody