TFEB Polyclonal Antibody
Product Sizes
60 ul
£319.00
RD90326A-60UL
120 ul
£479.00
RD90326A-120UL
200 ul
£761.00
RD90326A-200UL
About this Product
- SKU:
- RD90326A
- Additional Names:
- TFEB,ALPHATFEB,BHLHE35,TCFEB
- Application:
- Immunofluorescence, Immunohistochemistry, Western Blot
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This is a TFEB Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.|Transcription factor that acts as a master regulator of lysosomal biogenesis, autophagy, lysosomal exocytosis, lipid catabolism, energy metabolism and immune response. Specifically recognizes and binds E-box sequences (5'-CANNTG-3'; efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFE3 or MITF. Involved in the cellular response to amino acid availability by acting downstream of MTOR: in the presence of nutrients, TFEB phosphorylation by MTOR promotes its cytosolic retention and subsequent inactivation. Upon starvation or lysosomal stress, inhibition of MTOR induces TFEB dephosphorylation, resulting in nuclear localization and transcription factor activity.
- Host:
- Rabbit
- Immunogen:
- Recombinant fusion protein of human TFEB
- Isotype:
- IgG
- Molecular Weight:
- 48KDa
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Reddot
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:tfeb-polyclonal-antibody-29141.html
