MAPK8IP1 Polyclonal Antibody
Product Sizes
60 ul
£319.00
RD89954A-60UL
120 ul
£479.00
RD89954A-120UL
200 ul
£761.00
RD89954A-200UL
About this Product
- SKU:
- RD89954A
- Additional Names:
- MAPK8IP1,IB1,JIP-1,JIP1,PRKM8IP
- Application:
- Western Blot
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene encodes a regulator of the pancreatic beta-cell function. It is highly similar to JIP-1, a mouse protein known to be a regulator of c-Jun amino-terminal kinase (Mapk8). This protein has been shown to prevent MAPK8 mediated activation of transcription factors, and to decrease IL-1 beta and MAP kinase kinase 1 (MEKK1) induced apoptosis in pancreatic beta cells. This protein also functions as a DNA-binding transactivator of the glucose transporter GLUT2. RE1-silencing transcription factor (REST) is reported to repress the expression of this gene in insulin-secreting beta cells. This gene is found to be mutated in a type 2 diabetes family, and thus is thought to be a susceptibility gene for type 2 diabetes.|This is a MAPK8IP1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
- Host:
- Rabbit
- Immunogen:
- Recombinant fusion protein of human MAPK8IP1
- Isotype:
- IgG
- Molecular Weight:
- 110kDa
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Reddot
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:mapk8ip1-polyclonal-antibody-32713.html
