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Antibodies

PRCP Polyclonal Antibody

Product Sizes
60 ul
£319.00
RD89592A-60UL
120 ul
£479.00
RD89592A-120UL
200 ul
£761.00
RD89592A-200UL
About this Product
SKU:
RD89592A
Additional Names:
PRCP,HUMPCP,PCP
Application:
Western Blot
Buffer:
PBS
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
This gene encodes a member of the peptidase S28 family of serine exopeptidases. The encoded preproprotein is proteolytically processed to generate the mature lysosomal prolylcarboxypeptidase. This enzyme cleaves C-terminal amino acids linked to proline in peptides such as angiotension II, III and des-Arg9-bradykinin. The cleavage occurs at acidic pH, but the enzyme activity is retained with some substrates at neutral pH. This enzyme has been shown to be an activator of the cell matrix-associated prekallikrein. The importance of angiotension II, one of the substrates of this enzyme, in regulating blood pressure and electrolyte balance suggests that this gene may be related to essential hypertension. A pseudogene of this gene has been identified on chromosome 2. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.|This is a PRCP Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Host:
Rabbit
Immunogen:
Recombinant fusion protein of human PRCP
Isotype:
IgG
Molecular Weight:
80KDa
Purification:
Affinity Purified
Reactivities:
Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Reddot
Type:
Antibody: Polyclonal Antibody