(KO Validated) TYSY Polyclonal Antibody
Product Sizes
60 ul
£345.00
RD89442A-60UL
120 ul
£533.00
RD89442A-120UL
200 ul
£828.00
RD89442A-200UL
About this Product
- SKU:
- RD89442A
- Additional Names:
- TYMS, HST422, TMS, TS, thymidylate synthase
- Application:
- Immunofluorescence, Immunohistochemistry, Western Blot
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This is a (KO Validated) TYSY Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.|Thymidylate synthase catalyzes the methylation of deoxyuridylate to deoxythymidylate using 5,10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair. The enzyme has been of interest as a target for cancer chemotherapeutic agents. It is considered to be the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and some folate analogs. Expression of this gene and that of a naturally occuring antisense transcript rTSalpha (GeneID:55556) vary inversely when cell-growth progresses from late-log to plateau phase.
- Host:
- Rabbit
- Immunogen:
- Recombinant fusion protein of human TYSY
- Isotype:
- IgG
- Molecular Weight:
- 16KDa/80KDa
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Reddot
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:-ko-validated-tysy-polyclonal-antibody-29240.html
