CRTC1 Polyclonal Antibody
Product Sizes
60 ul
£319.00
RD88192A-60UL
120 ul
£479.00
RD88192A-120UL
200 ul
£761.00
RD88192A-200UL
About this Product
- SKU:
- RD88192A
- Additional Names:
- CRTC1,MECT1,TORC-1,TORC1,WAMTP1
- Application:
- Western Blot
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This is a CRTC1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.|Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PGC1alpha and inducer of mitochondrial biogenesis in muscle cells. In the hippocampus, involved in late-phase long-term potentiation (L-LTP maintenance at the Schaffer collateral-CA1 synapses. May be required for dendritic growth of developing cortical neurons (By similarity. In concert with SIK1, regulates the light-induced entrainment of the circadian clock. In response to light stimulus, coactivates the CREB-mediated transcription of PER1 which plays an important role in the photic entrainment of the circadian clock.
- Host:
- Rabbit
- Immunogen:
- Recombinant fusion protein of human CRTC1
- Isotype:
- IgG
- Molecular Weight:
- 80-85kDa
- Purification:
- Affinity Purified
- Reactivities:
- Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Reddot
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:crtc1-polyclonal-antibody-31440.html
