FAM3B Polyclonal Antibody
Product Sizes
60 ul
£319.00
RD87803A-60UL
120 ul
£479.00
RD87803A-120UL
200 ul
£761.00
RD87803A-200UL
About this Product
- SKU:
- RD87803A
- Additional Names:
- FAM3B,2-21,C21orf11,C21orf76,ORF9,PANDER,PRED44
- Application:
- Western Blot
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- FAM3B, also known as Pancreatic-derived factor (PANDER), is an islet-specific secreted cytokine specifically expressed at high levels in the islets of Langerhans of the endocrine pancreas. FAM3B can induce apoptosis of alpha and beta cells in a dose- and time-dependent manner. Previous studies showed that FAM3B regulates glucose and lipid metabolism through interaction with liver and endocrine pancreas. FAM3B silencing activates both extrinsic and intrinsic apoptotic pathways. In general, silencing FAM3B promoted p53 phosphorylation and induced p53 accumulation by decreasing Mdm2 expression, which resulted in apoptotic cell death.|This is a FAM3B Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
- Host:
- Rabbit
- Immunogen:
- Recombinant fusion protein of human FAM3B
- Isotype:
- IgG
- Molecular Weight:
- 71kDa
- Purification:
- Affinity Purified
- Reactivities:
- Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Reddot
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:fam3b-polyclonal-antibody-31086.html
