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Antibodies

SMPD3 Polyclonal Antibody

Product Sizes
60 ul
£319.00
RD87188A-60UL
120 ul
£479.00
RD87188A-120UL
200 ul
£761.00
RD87188A-200UL
About this Product
SKU:
RD87188A
Additional Names:
SMPD3,NSMASE2
Application:
Western Blot
Buffer:
PBS
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
Catalyzes the hydrolysis of sphingomyelin to form ceramide and phosphocholine. Ceramide mediates numerous cellular functions, such as apoptosis and growth arrest, and is capable of regulating these 2 cellular events independently. Also hydrolyzes sphingosylphosphocholine. Regulates the cell cycle by acting as a growth suppressor in confluent cells. Probably acts as a regulator of postnatal development and participates in bone and dentin mineralization. Binds to anionic phospholipids (APLs such as phosphatidylserine (PS and phosphatidic acid (PA that modulate enzymatic activity and subcellular location. May be involved in IL-1-beta-induced JNK activation in hepatocytes (By similarity. May act as a mediator in transcriptional regulation of NOS2/iNOS via the NF-kappa-B activation under inflammatory conditions (By similarity.|This is a SMPD3 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Host:
Rabbit
Immunogen:
Recombinant fusion protein of human SMPD3
Isotype:
IgG
Molecular Weight:
95kDa
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Reddot
Type:
Antibody: Polyclonal Antibody