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Antibodies

Recombinant XBP1 Monoclonal Antibody

Product Sizes
50 ul
£265.00
RD87095A-50UL
100 ul
£399.00
RD87095A-100UL
About this Product
SKU:
RD87095A
Additional Names:
Tax responsive element binding protein 5,Tax-responsive element-binding protein 5,TREB5,X box binding protein 1,X box binding protein 2,X-box-binding protein 1,XBP 1,XBP-1,XBP1,XBP1,XBP2
Application:
Western Blot
Buffer:
50mm tris-glycine
Clonality:
Monoclonal
Concentration:
300 ug/ml
Extra Details:
This gene encodes a transcription factor that regulates MHC class II genes by binding to a promoter element referred to as an X box. This gene product is a bZIP protein, which was also identified as a cellular transcription factor that binds to an enhancer in the promoter of the T cell leukemia virus type 1 promoter. It may increase expression of viral proteins by acting as the DNA binding partner of a viral transactivator. It has been found that upon accumulation of unfolded proteins in the endoplasmic reticulum (ER), the mRNA of this gene is processed to an active form by an unconventional splicing mechanism that is mediated by the endonuclease inositol-requiring enzyme 1 (IRE1). The resulting loss of 26 nt from the spliced mRNA causes a frame-shift and an isoform XBP1(S), which is the functionally active transcription factor.|This is a Recombinant XBP1 Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.
Host:
Rabbit
Immunogen:
Recombinant protein of human XBP1
Isotype:
IgG
Molecular Weight:
65kDa
Purification:
Affinity Purified
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Reddot
Type:
Antibody: Monoclonal Antibody